Gut microbiota and carcinogenesis in various human organs

نویسندگان

چکیده

Scientific research in recent years has revealed a significant role of the human microbiome carcinogenesis. These data served as rationale for inclusion polymorphic microbiomes key characteristics carcinogenesis an important mechanistic determinant cancer, addition to other fundamental biological processes manifested during multi-stage The gastrointestinal tract is most actively involved pathogenesis malignant neoplasms digestive system due changes quantitative and qualitative composition microbiota, increase production genotoxic bacterial metabolites factors This review also addresses lung associated mainly with short-chain fatty aicids, breast endometrial cancers specific community towar)ds species metabolism estrogen precursors. probable mechanisms microorganisms participation development prostate cancer (the effect lipopolysaccharides, antibiotics deconjugated estrogen) are considered.
 Data on relationship between metabolic various sites open up perspectives its use diagnosis, treatment prevention justify need further this area.

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ژورنال

عنوان ژورنال: Journal of Microbiology, Epidemiology and Immunobiology

سال: 2023

ISSN: ['0372-9311', '2686-7613']

DOI: https://doi.org/10.36233/0372-9311-310